Entertainment

Christina Applegate says she has been diagnosed with multiple sclerosis

christina applegate
Christina Applegate. Amy Sussman/Getty Images
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The actor Christina Applegate has shared that she has multiple sclerosis.

She tweeted early Tuesday: "Hi friends. A few months ago I was diagnosed with MS. It's been a strange journey. But I have been so supported by people that I know who also have this condition. It's been a tough road. But as we all know, the road keeps going. Unless some asshole blocks it."

The US National Institute of Neurological Disorders and Stroke describes multiple sclerosis as "an unpredictable disease of the central nervous system" that can "range from relatively benign to somewhat disabling to devastating, as communication between the brain and other parts of the body is disrupted."

"The vast majority of patients are mildly affected, but in the worst cases, MS can render a person unable to write, speak, or walk," it says. "MS is a disease with a natural tendency to remit spontaneously, for which there is no universally effective treatment."

Applegate is known for her TV and film roles such as "Married... with Children," and "Anchorman: The Legend of Ron Burgundy."

Christina Applegate Dead to Me Netflix series
Christina Applegate in "Dead to Me."  Saeed Adyani/Netflix

Most recently, she played a widower in Netflix's 2019 drama series "Dead to Me." She told The Hollywood Reporter at the time that she asked for her mastectomy to be written into the show.

Applegate was diagnosed with an early stage of breast cancer in 2008. She decided to undergo a double mastectomy after learning she had the BRCA1 gene, which can make it more likely to contract breast cancer.

"Her having a mastectomy was something I brought to [showrunner] Liz [Feldman] in the middle of filming. I was trying to figure out this core pain that she has, and I thought we never really see women in television or in film really being [shown] having had this surgery," Applegate told THR.

She went on to receive nominations for a Golden Globe, SAG award, and Critics' Choice award for the role.

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Tom Murray is a former Entertainment Editor at Insider's London bureau where he covered TV, movies, and celebrity culture. Before moving to entertainment, Tom was a lifestyle reporter writing features on celebrity liquor brandsSri Lankan train travelmen's skincare mistakes and rare liquor hunters. And before becoming a reporter, Tom gained an invaluable insight into finding what our audience loves, working on the social media team for two years. He graduated with a degree in history from the University of Nottingham, where he was the editor of the student news website The Tab Nottingham. Email Tom at tmurray@bjinnox.com or find him on Twitter at @tom_murray3.
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Sinéad Baker
Sinéad Baker is a Military and Defense Correspondent based in Business Insider's London bureau, writing about Russia's invasion of Ukraine and NATO actions.Sinéad most often covers soldiers' experiences, military strategy, battlefield developments, weapons systems, the defense industry's response, and the impact on NATO and European security, and geopolitical decisions that surround the Ukraine war. She has reported from NATO’s frontlines and around Europe,  has interviewed multiple prime ministers and defense ministers, has appeared on BBC News and The Guardian's politics podcast, and has been cited by Congressional hearings.Sinéad has also extensively covered US politics and previously led Business Insider's breaking news coverage from London.Sinéad previously completed a master's degree in investigative journalism at City, University of London, and has written for The Guardian, The Observer, and TheJournal.ie. Sinéad is the former editor of the multi-award-winning The University Times in Dublin.Expertise
  • Experiences of soldiers in Ukraine, including battlefield developments and tactics
  • Western military responses to the war, and lessons they should learn
  • New weaponry built for and in response to the war 
Email Sinéad at sbaker@bjinnox.com or find her on X.